Ketohexokinase Protein (KHK) (His tag)
Quick Overview for Ketohexokinase Protein (KHK) (His tag) (ABIN7318703)
Target
See all Ketohexokinase (KHK) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Ketohexokinase protein is labelled with His tag.
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Purpose
- Recombinant Human Ketohexokinase/KHK Protein (His Tag)
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Sequence
- Met 1-Val298
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Characteristics
- Recombinant Human Ketohexokinase is produced by our Mammalian expression system and the target gene encoding Met1-Val298 is expressed with a 6His tag at the C-terminus.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 50nM KCl, 10 % Glycerol, pH 7.4.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Expiry Date
- 6 months
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- Ketohexokinase (KHK)
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Alternative Name
- Ketohexokinase/KHK
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Background
- Hepatic fructokinase,KHK,Ketohexokinase,Ketohexokinase, also known as Hepatic fructokinase, is a member of the carbohydrate kinase PfkB family. It exits as a homodimer and most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.This enzyme catalyzes conversion of fructose to fructose-1-phosphate. It is the first enzyme with a specialized pathway that catabolizes dietary fructose. Defects in KHK are the cause of fructosuria.
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Molecular Weight
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Calculated MW: 33.7 kDa
Observed MW: 30 kDa
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Gene ID
- 3795
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UniProt
- P50053
Target
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