KIF1BP Protein (His-GST)

Catalog No. ABIN7317164

This Recombinant KIF1BP protein is expressed in Baculovirus infected Insect Cells.

Quick Overview for KIF1BP Protein (His-GST) (ABIN7317164)

Target: KIF1BP (KIAA1279) (KIAA1279)

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Purity: > 90 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This KIF1BP protein is labelled with His-GST.

Purpose: Recombinant Human KIAA1279 Protein (His & GST Tag)

Sequence: Met 1-Thr621

Characteristics: A DNA sequence encoding the human KIAA1279 (Q96EK5) (Met1-Thr621) was expressed with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: KIF1BP (KIAA1279) (KIAA1279)

Alternative Name: KIAA1279

Background: KBP,KIAA1279,TTC20,KIFBP (Kinesin Family Binding Protein, also known as KIAA1279 and KIF1BP) is a Protein Coding gene. This gene encodes a kinesin family member 1 binding protein that is characterized by two tetratricopeptide repeats. The encoded protein localizes to the mitochondria and may be involved in regulating the transport of the mitochondria. Homozygous nonsense mutations in KIAA1279 at 1q22.1, encoding a protein with two tetratricopeptide repeats, underlie this syndromic form of Hirschsprung disease and generalized polymicrogyria, establishing the importance of KIAA1279 in both enteric and central nervous system development. KIAA1279 is widely expressed in the brain, testis, and other tissues. Diseases associated with KIFBP include Goldberg-Shprintzen Syndrome and Shprintzen-Goldberg Craniosynostosis Syndrome.

Molecular Weight:

Calculated MW: 99.6 kDa

Observed MW: 92-102 kDa

Gene ID: 26128

UniProt: Q96EK5