LUM Protein (His tag)
Quick Overview for LUM Protein (His tag) (ABIN7318743)
Target
See all LUM ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This LUM protein is labelled with His tag.
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Purpose
- Recombinant Human Lumican/LUM Protein (His Tag)
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Sequence
- Gln19-Asn338
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Characteristics
- Recombinant Human Lumican is produced by our Mammalian expression system and the target gene encoding Gln19-Asn338 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Lumican (LUM) (AA 1-338) protein (GST tag)
LUM Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Lumican (LUM) protein (His tag)LUM Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH 7.2.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- LUM (Lumican (LUM))
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Alternative Name
- Lumican/LUM
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Background
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Background: Lumican is a 40 kD secreted protein which belongs to the small leucine-rich repeat proteoglycans (SLRPs) and the class II subfamily. Human Lumican is synthesized as a 338 amino acid precursor then cut the 18 aa signal sequence. The mature Human Lumican contains 12 leucine-rich repeats (LRRs), 4 potential sites of N-linked glycosylation, and a C- terminal with two conserved cyst-eines. Lumican can be existed in extracellular matrix of human articular cartilage. Lumican participates in the maintenance of tissue homeostasis and regulates cellular functions in vivo, such as cell proliferation, adhesion, migration, and differentiation. The overexpression of lumican has been correlated to colorectal tumor, breast, neuroendocrine, and pancreatic cancers.
Synonym: Lumican, Keratan Sulfate Proteoglycan Lumican, KSPG Lumican, LUM, LDC, SLRR2D
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Molecular Weight
- 37.7 kDa
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UniProt
- P51884
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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