Quick Overview for LUM Protein (His tag) (ABIN7320810)
Target
See all LUM ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This LUM protein is labelled with His tag.
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Purpose
- Recombinant Mouse Lumican/LUM Protein (His Tag)
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Sequence
- Gln19-Asn338
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Characteristics
- Recombinant Mouse Lumican is produced by our Mammalian expression system and the target gene encoding Gln19-Asn338 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Lumican (LUM) (AA 1-338) protein (GST tag)
LUM Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- LUM (Lumican (LUM))
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Alternative Name
- Lumican/LUM
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Background
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Background: Keratan sulfate proteoglycan lumican, mostly known as lumican, belongs to the SLRP class II subfamily and the small leucine-rich proteoglycan (SLRP) family. Lumican binds to laminin. It has positive regulation of transcription from RNA polymerase II promoter and transforming growth factor beta1 production. Lumican is expressed in a variety of tissues, including skin, artery, lung, cornea, kidney, bone, aorta, and articular cartilage. The abnormal connective tissue phenotype seen in the Lumican null mice shows the importance of the role of Lumican in collagen fibrillogenesis. In addition to the control of collagen fibril assembly, Lumican has been shown to play a role in the regulation of cell proliferation, migration, and adhesion.
Synonym: Keratan sulfate proteoglycan lumican,KSPG lumican,Lumican, LDC
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Molecular Weight
- 37.4 kDa
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UniProt
- P51885
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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