MYOC Protein (His tag)
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- Target See all MYOC Proteins
- MYOC (Myocilin (MYOC))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MYOC protein is labelled with His tag.
- Purpose
- Recombinant Human MYOC/Myocilin Protein (His Tag)
- Sequence
- Met 1-Met 504
- Characteristics
- A DNA sequence encoding the full length of human MYOC (Q99972) (Met 1-Met 504) was fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product MYOC Protein
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Myocilin (MYOC) (AA 1-504) protein (GST tag)
MYOC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Myocilin (MYOC) (AA 36-135) protein (GST tag)MYOC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Myocilin (MYOC) (AA 227-504) protein (His tag)Crystallography grade MYOC Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Myocilin (MYOC) (AA 33-226) protein (His tag)Crystallography grade MYOC Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Myocilin (MYOC) (AA 19-212) protein (His tag)Crystallography grade MYOC Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Myocilin (MYOC) (AA 213-490) protein (His tag)Crystallography grade MYOC Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Myocilin (MYOC) (AA 33-504) protein (His tag)Crystallography grade MYOC Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Myocilin (MYOC) (AA 19-490) protein (His tag)Crystallography grade MYOC Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Myocilin (MYOC) protein (Myc-DYKDDDDK Tag)MYOC Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- MYOC (Myocilin (MYOC))
- Alternative Name
- MYOC/Myocilin (MYOC Products)
- Synonyms
- MYOC Protein, MGC136645 Protein, zgc:136645 Protein, AI957332 Protein, GLC1A Protein, TIGR Protein, GPOA Protein, JOAG Protein, JOAG1 Protein, myocilin Protein, Tigr Protein, myocilin Protein, MYOC Protein, myoc Protein, Myoc Protein
- Background
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Background: Myocilin, also known as Trabecular meshwork-induced glucocorticoid response protein, MYOC and GLC1A, is a protein which contains one olfactomedin-like domain. Myocilin / MYOC may participate in the obstruction of fluid outflow in the trabecular meshwork. Myocilin / MYOC is expressed in large amounts in various types of muscle, ciliary body, papillary sphincter, skeletal muscle, heart and other tissues. Myocilin / MYOC is expressed predominantly in the retina. In normal eyes, it is found in the inner uveal meshwork region and the anterior portion of the meshwork. In contrast, in many glaucomatous eyes, it is found in more regions of the meshwork and appeared more intensively than in normal eyes, regardless of the type or clinical severity of glaucoma. Defects in Myocilin / MYOC may contribute to primary congenital glaucoma type 3A (GLC3A). Defects in MYOC may also contribute to this phenotype via digenic inheritance. GLC3A is an autosomal recessive form of primary congenital glaucoma (PCG). PCG is characterized by marked increase of intraocular pressure at birth or early choldhood, large ocular globes (buphthalmos) and corneal edema.
Synonym: GLC1A;GPOA;JOAG;JOAG1;myocilin;TIGR
- Molecular Weight
- 54.7 kDa
- UniProt
- Q99972
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