MYOZ2 Protein (His tag)
Quick Overview for MYOZ2 Protein (His tag) (ABIN7318797)
Target
See all MYOZ2 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This MYOZ2 protein is labelled with His tag.
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Purpose
- Recombinant Human Myozenin-2/MYOZ2 Protein (His Tag)
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Sequence
- Met 1-Leu264
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Characteristics
- Recombinant Human Myozenin-2 is produced by our E.coli expression system and the target gene encoding Met1-Leu264 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 10 mM Tris, pH 8.0.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- MYOZ2 (Myozenin 2 (MYOZ2))
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Alternative Name
- Myozenin-2/MYOZ2
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Background
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Background: Myozenin 2 (MYOZ2) is a 264 amino acid protein that belongs to the myozenin family. MYOZ2 binds to Calcineurin, a phosphatase that is involved in calcium-dependent signal transduction in diverse cell types. MYOZ2 is one of the sarcomeric proteins and plays an important role in myofibrillogenesis and the modulation of calcineurin signaling. It may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and plays an important role in the modulation of calcineurin signaling. Defects in MYOZ2 are the cause of familial hypertrophic cardiomyopathy type 16 (CMH16), a hereditary heart disorder.
Synonym: Myozenin-2, Calsarcin-1, FATZ-Related Protein 2, MYOZ2, C4orf5
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Molecular Weight
- 30.9 kDa
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UniProt
- Q9NPC6
Target
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