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Neurexophilin 1 Protein (NXPH1) (His tag)

NXPH1 Origin: Rat Host: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE
Catalog No. ABIN7321231
  • Target See all Neurexophilin 1 (NXPH1) Proteins
    Neurexophilin 1 (NXPH1)
    Protein Type
    Recombinant
    Origin
    • 6
    • 2
    • 1
    • 1
    Rat
    Source
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Neurexophilin 1 protein is labelled with His tag.
    Purpose
    Recombinant Rat Neurexophilin-1/NXPH1 Protein (His Tag)
    Sequence
    Met 1-Gly 271
    Characteristics
    A DNA sequence encoding the rat NXPH1 (Q63366-1) (Met 1-Gly 271) was expressed, fused with a polyhistidine tag at the C-terminus.
    Purity
    > 92 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method
    Top Product
    Discover our top product NXPH1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Neurexophilin 1 (NXPH1)
    Alternative Name
    Neurexophilin-1/NXPH1 (NXPH1 Products)
    Synonyms
    zgc:101108 Protein, C130005L03Rik Protein, NPH1 Protein, neurexophilin 1 Protein, nxph1 Protein, NXPH1 Protein, Nxph1 Protein
    Background

    Background: Neurexophilin-1, or NXPH1 is a secreted glycoprotein, which belongs to the Neurexophilin family. The Neurexophilin family contain at least four genes and resembles a neuropeptide, suggesting a function as an endogenous ligand for alpha-neurexins. The mammalian brains contain four genes for neurexophilins the products of which share a common structure composed of five domains: an N-terminal signal peptide, a variable N-terminal domain, a highly conserved central domain that is N-glycosylated, a short linker region, and a conserved C-terminal domain that is cysteine-rich. Neurexophilin-1 constitutes a secreted cysteine-rich glycoprotein, forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons. Neurexophilins 1 and 3 but not 4 (neurexophilin 2 is not expressed in rodents) bind to a single individual LNS domain, the second overall LNS domain in all three alpha-neurexins.

    Synonym: MGC124635

    Molecular Weight
    30 kDa
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