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NHP2 Protein (His tag)

NHP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318843
  • Target See all NHP2 Proteins
    NHP2 (NHP2 Ribonucleoprotein (NHP2))
    Protein Type
    Recombinant
    Origin
    • 4
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This NHP2 protein is labelled with His tag.
    Purpose
    Recombinant Human NHP2/NOLA2 Protein (His Tag)
    Sequence
    Met 1-Leu153
    Characteristics
    Recombinant Human Nucleolar protein family A member 2 is produced by our E.coli expression system and the target gene encoding Met1-Leu153 is expressed with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product NHP2 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM Tris,100 mM NaCl,1 mM DTT, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    NHP2 (NHP2 Ribonucleoprotein (NHP2))
    Alternative Name
    NHP2/NOLA2 (NHP2 Products)
    Synonyms
    DKCB2 Protein, NHP2P Protein, NOLA2 Protein, 2410130M07Rik Protein, D11Ertd175e Protein, Nola2 Protein, NHP2 ribonucleoprotein Protein, NHP2 Protein, Nhp2 Protein
    Background

    Background: NHP2 belongs to the H/ACA snoRNPs gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been organized into 2 families: C/D and H/ACA. NHP2 forms a small ribonucleoprotein particle with GAR1 (NOLA1). NHP2 is involved in a variety of aspects of rRNA processing and modification. NHP2 localizes to the dense fibrillar component of the nucleolus and in nuclear Cajal bodies. NHP2 may also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

    Synonym: H/ACA ribonucleoprotein complex subunit 2, Nucleolar protein family A member 2, snoRNP protein NHP2, NHP2, NOLA2, NHP2P.

    Molecular Weight
    19.3 kDa
    UniProt
    Q9NX24
    Pathways
    Telomere Maintenance
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