NUCB2 Protein
Quick Overview for NUCB2 Protein (ABIN7319510)
Target
See all NUCB2 ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Human Nucleobindin-2/NUCB2 Protein
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Sequence
- Val25-Leu106
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Characteristics
- Recombinant Human Nucleobindin-2 is produced by our E.coli expression system and the target gene encoding Val25-Leu106 is expressed.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 10 mM Sodium Phosphate, pH 6.5.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- NUCB2 (Nucleobindin 2 (NUCB2))
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Alternative Name
- Nucleobindin-2/NUCB2
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Background
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Background: Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulation of hunger and fat storage. Nesfatin-1 is also expressed in other areas of the brain, and in pancreatic islets β-cells, gastric endocrine cells and adipocytes. Nesfatin-1 suppresses food intake and can regulate energy metabolism in a Leptin independent manner. Nesfatin-1 may also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance.
Synonym: Nucleobindin-2, DNA-binding protein NEFA, Gastric cancer antigen Zg4, Prepronesfatin, Nesfatin-1, NUCB2, NEFA
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Molecular Weight
- 9.6 kDa
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UniProt
- P80303
Target
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