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NUCB2 Protein

This Recombinant NUCB2 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7319510

Quick Overview for NUCB2 Protein (ABIN7319510)

Target

See all NUCB2 Proteins
NUCB2 (Nucleobindin 2 (NUCB2))

Protein Type

Recombinant

Origin

  • 6
  • 4
  • 2
Human

Source

  • 10
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purpose

    Recombinant Human Nucleobindin-2/NUCB2 Protein

    Sequence

    Val25-Leu106

    Characteristics

    Recombinant Human Nucleobindin-2 is produced by our E.coli expression system and the target gene encoding Val25-Leu106 is expressed.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 10 mM Sodium Phosphate, pH 6.5.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    NUCB2 (Nucleobindin 2 (NUCB2))

    Alternative Name

    Nucleobindin-2/NUCB2

    Background

    Background: Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulation of hunger and fat storage. Nesfatin-1 is also expressed in other areas of the brain, and in pancreatic islets β-cells, gastric endocrine cells and adipocytes. Nesfatin-1 suppresses food intake and can regulate energy metabolism in a Leptin independent manner. Nesfatin-1 may also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance.

    Synonym: Nucleobindin-2, DNA-binding protein NEFA, Gastric cancer antigen Zg4, Prepronesfatin, Nesfatin-1, NUCB2, NEFA

    Molecular Weight

    9.6 kDa

    UniProt

    P80303
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