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PTH Protein

This Recombinant PTH protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7318866

Quick Overview for PTH Protein (ABIN7318866)

Target

See all PTH Proteins
PTH (Parathyroid Hormone (PTH))

Protein Type

Recombinant

Origin

  • 20
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Human

Source

  • 21
  • 8
  • 2
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purpose

    Recombinant Human Parathyroid Hormone/PTH Protein (1-84)

    Sequence

    Ser32-Gln115

    Characteristics

    Recombinant Human Parathyroid Hormone is produced by our E.coli expression system and the target gene encoding Ser32-Gln115 is expressed. 

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 10 mM HAc-NaAc, 150 mM NaCl, 5 % Mannitol, pH 4.0.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    PTH (Parathyroid Hormone (PTH))

    Alternative Name

    Parathyroid Hormone/PTH

    Target Type

    Hormone

    Background

    Background: Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone, parathyroid hormone-related protein, binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone. After intracellular processing, the mature hormone is packaged within the Golgi into secretory vesicles, the secreted into blood by exocytosis. Parathyroid hormone is secreted as a linear protein of 84 amino acids.

    Synonym: Parathyroid Hormone, PTH, Parathormone, Parathyrin,PTH1

    Molecular Weight

    9.0 kDa

    UniProt

    P01270

    Pathways

    cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
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