Peroxiredoxin 4 Protein (PRDX4) (His tag)

Catalog No. ABIN7318891

This Recombinant Peroxiredoxin 4 protein is produced in Escherichia coli (E. coli).

Quick Overview for Peroxiredoxin 4 Protein (PRDX4) (His tag) (ABIN7318891)

Target: Peroxiredoxin 4 (PRDX4)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This Peroxiredoxin 4 protein is labelled with His tag.

Purpose: Recombinant Human Peroxiredoxin-4/PRDX4 Protein (His Tag)

Sequence: Trp38-Asn271

Characteristics: Recombinant Human Peroxiredoxin-4 is produced by our E.coli expression system and the target gene encoding Trp38-Asn271 is expressed with a 6His tag at the N-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM DTT, pH 7.2.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: Peroxiredoxin 4 (PRDX4)

Alternative Name: Peroxiredoxin-4/PRDX4

Background:

Background: Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.

Synonym: Peroxiredoxin-4, Antioxidant Enzyme AOE372, AOE37-2, Peroxiredoxin IV, Prx-IV, Thioredoxin Peroxidase AO372, Thioredoxin-Dependent Peroxide Reductase A0372, PRDX4

Molecular Weight: 33.8 kDa

UniProt: Q13162