PFKM Protein (His tag)
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- Target See all PFKM Proteins
- PFKM (phosphofructokinase, Muscle (PFKM))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This PFKM protein is labelled with His tag.
- Purpose
- Recombinant Human PFK1/PFKM Protein (His Tag)
- Sequence
- Thr 2-Val 780
- Characteristics
- Recombinant Human PhosphoFructoKinase, Muscle type is produced by our Mammalian expression system and the target gene encoding Thr2-Val780 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PFKM Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- PFKM (phosphofructokinase, Muscle (PFKM))
- Alternative Name
- PFK1/PFKM (PFKM Products)
- Background
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Background: 6-phosphofructokinase, muscle type is a muscle-type isozyme that in humans is encoded by the PFKM gene. It belongs to the phosphofructokinase family and Two domains subfamily. PFKM functions as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP.
Synonym: 6-phosphofructokinase, muscle type,Phosphofructo-1-kinase isozyme A,Phosphofructokinase 1,Phosphohexokinase,PFKM,PFKX,ATP-PFK,GSD7,PFK-1,PFK1,PFKA,PPP1R122
- Molecular Weight
- 86.1 kDa
- UniProt
- P08237
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effect
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