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PMM1 Protein (His tag)

PMM1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318899
  • Target See all PMM1 Proteins
    PMM1 (Phosphomannomutase 1 (PMM1))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PMM1 protein is labelled with His tag.
    Purpose
    Recombinant Human PMM1 Protein (His Tag)
    Sequence
    Met 1-Ala262
    Characteristics
    Recombinant Human Phosphomannomutase 1 is produced by our E.coli expression system and the target gene encoding Met1-Ala262 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PMM1 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 1 mM DTT, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    PMM1 (Phosphomannomutase 1 (PMM1))
    Alternative Name
    PMM1 (PMM1 Products)
    Synonyms
    Sec53 Protein, C77612 Protein, phosphomannomutase 1 Protein, phosphomannomutase 1 L homeolog Protein, PMM1 Protein, pmm1 Protein, Pmm1 Protein, pmm1.L Protein
    Background

    Background: Phosphomannomutase 1 (PMM1) blongs to the eukaryotic PMM family. Phosphomannomutase 1 can catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose which required for a number of critical mannosyl transfer reactions. PMM1 is highly expressed in liver, heart, brain, and pancreas, but lower expression in skeletal muscle. In addition, PMM1 may be responsible for the degradation of glucose-1,6 bisphosphate in ischemic brain.

    Synonym: Phosphomannomutase 1, PMM 1, PMMH-22, PMM1, PMMH22

    Molecular Weight
    30.8 kDa
    UniProt
    Q92871
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