PSPH Protein (His tag)
Quick Overview for PSPH Protein (His tag) (ABIN7318903)
Target
See all PSPH ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This PSPH protein is labelled with His tag.
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Purpose
- Recombinant Human PSPH Protein (His Tag)
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Sequence
- Met 1-Glu225
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Characteristics
- Recombinant Human Phosphoserine Phosphatase is produced by our E.coli expression system and the target gene encoding Met1-Glu225 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 50 mM Tris, 250 mM NaCl, 50 mM Imidazole, pH 8.5 .
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- PSPH (Phosphoserine Phosphatase (PSPH))
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Alternative Name
- PSPH
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Background
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Background: Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. Deficiency of this protein is thought to be linked to Williams syndrome. A disorder that results in pre- and postnatal growth retardation, moderate psychomotor retardation and facial features suggestive of Williams syndrome.
Synonym: Phosphoserine Phosphatase, PSP, PSPase, L-3-Phosphoserine Phosphatase, O-Phosphoserine Phosphohydrolase, PSPH
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Molecular Weight
- 26.1 kDa
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UniProt
- P78330
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Pathways
- Warburg Effect
Target
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