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PSPH Protein (His tag)

This Recombinant PSPH protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7318903
$345.12
Plus shipping costs $50.00
Shipping to: United States
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Quick Overview for PSPH Protein (His tag) (ABIN7318903)

Target

See all PSPH Proteins
PSPH (Phosphoserine Phosphatase (PSPH))

Protein Type

Recombinant

Origin

  • 9
  • 2
  • 1
  • 1
  • 1
Human

Source

  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This PSPH protein is labelled with His tag.

    Purpose

    Recombinant Human PSPH Protein (His Tag)

    Sequence

    Met 1-Glu225

    Characteristics

    Recombinant Human Phosphoserine Phosphatase is produced by our E.coli expression system and the target gene encoding Met1-Glu225 is expressed with a 6His tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of 50 mM Tris, 250 mM NaCl, 50 mM Imidazole, pH 8.5 .

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    PSPH (Phosphoserine Phosphatase (PSPH))

    Alternative Name

    PSPH

    Background

    Background: Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. Deficiency of this protein is thought to be linked to Williams syndrome. A disorder that results in pre- and postnatal growth retardation, moderate psychomotor retardation and facial features suggestive of Williams syndrome.

    Synonym: Phosphoserine Phosphatase, PSP, PSPase, L-3-Phosphoserine Phosphatase, O-Phosphoserine Phosphohydrolase, PSPH

    Molecular Weight

    26.1 kDa

    UniProt

    P78330

    Pathways

    Warburg Effect
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