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PSPH Protein (His tag)

This Recombinant PSPH protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7318903

Quick Overview for PSPH Protein (His tag) (ABIN7318903)

Target

See all PSPH Proteins
PSPH (Phosphoserine Phosphatase (PSPH))

Protein Type

Recombinant

Origin

  • 8
  • 2
  • 1
  • 1
  • 1
Human

Source

  • 4
  • 3
  • 3
  • 2
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This PSPH protein is labelled with His tag.

    Purpose

    Recombinant Human PSPH Protein (His Tag)

    Sequence

    Met 1-Glu225

    Characteristics

    Recombinant Human Phosphoserine Phosphatase is produced by our E.coli expression system and the target gene encoding Met1-Glu225 is expressed with a 6His tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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    Product
    Expression System
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
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  • Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of 50 mM Tris, 250 mM NaCl, 50 mM Imidazole, pH 8.5 .

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    PSPH (Phosphoserine Phosphatase (PSPH))

    Alternative Name

    PSPH

    Background

    Background: Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. Deficiency of this protein is thought to be linked to Williams syndrome. A disorder that results in pre- and postnatal growth retardation, moderate psychomotor retardation and facial features suggestive of Williams syndrome.

    Synonym: Phosphoserine Phosphatase, PSP, PSPase, L-3-Phosphoserine Phosphatase, O-Phosphoserine Phosphohydrolase, PSPH

    Molecular Weight

    26.1 kDa

    UniProt

    P78330

    Pathways

    Warburg Effect
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