Quick Overview for PVRIG Protein (His tag) (ABIN7321047)
Target
See all PVRIG ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This PVRIG protein is labelled with His tag.
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Purpose
- Recombinant Cynomolgus PVRIG (C-6His)
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Sequence
- Thr41-Asp171
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Characteristics
- Recombinant Cynomolgus Transmembrane Protein PVRIG is produced by our Mammalian expression system and the target gene encoding Thr41-Asp171 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) (Active) protein (hFc Tag)
PVRIG Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) (Active) protein (His tag)PVRIG Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 1-326) protein (His tag)custom-made PVRIG Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (Active) protein (mFc Tag)PVRIG Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 35-165) (Active) protein (hFc-Avi Tag)PVRIG Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 35-165) (Active) protein (hFc-Avi Tag,Biotin)PVRIG Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) protein (DYKDDDDK Tag)PVRIG Origin: Human Host: HEK-293 Cells Synthetic Nanodisc ELISA, Imm, cryo-EM, PhD, SPR
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) (Active) protein (His tag)PVRIG Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 99-330) protein (Fc Tag)PVRIG Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 38-326) protein (GST tag)PVRIG Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- PVRIG (Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG))
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Alternative Name
- PVRIG
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Background
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Background: PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The extracellular domain sequence of human and mouse PVRIG have approximately 65 % similarity. PVRIG functions as a cell surface receptor for Nectin-2/CD112, a cell surface protein that is widely expressed on antigen-presenting cells and tumor cells. Disrupting the PVRIG/Nectin-2 interaction enhances human T cell response, suggesting PVRIG is a novel checkpoint for human T cells. PVRIG may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
Synonym: C7orf15, CD112R, PVRIG, transmembrane protein PVRIG, C7orf15MGC138295, MGC104322, MGC138297, MGC2463
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Molecular Weight
- 14.5 kDa
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UniProt
- A0A2K5WVV8
Target
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