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PDYN Protein (AA 21-254) (His tag)

This Recombinant PDYN protein is expressed in HEK-293 Cells.
Catalog No. ABIN7319493
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Quick Overview for PDYN Protein (AA 21-254) (His tag) (ABIN7319493)

Target

See all PDYN Proteins
PDYN (Prodynorphin (PDYN))

Protein Type

Recombinant

Origin

Human

Source

  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 21-254

    Purification tag / Conjugate

    This PDYN protein is labelled with His tag.

    Purpose

    Recombinant Human Proenkephalin-B/PDYN Protein (His Tag)

    Sequence

    Asp21-Ala254

    Characteristics

    Recombinant Human Proenkephalin-B is produced by our Mammalian expression system and the target gene encoding Asp21-Ala254 is expressed with a 6His tag at the C-terminus.

    Sterility

    0.2 μm filtered

    Endotoxin Level

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    PDYN (Prodynorphin (PDYN))

    Alternative Name

    Proenkephalin-B/PDYN

    Background

    ADCA,Big Dyn,Dynorphin B,PDYN,PENKB,SCA23,Proenkephalin-B(PDYN), belongs to the opioid neuropeptide precursor family. The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing. Leu-enkephalins, which is a type of Proenkephalin-B, compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A has a typical opiod activity, it is 700 times more potent than Leu-enkephalin.

    Molecular Weight

    Calculated MW: 27.3 kDa

    Observed MW: 35 kDa

    Gene ID

    5173

    UniProt

    P01213
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