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PRM2 Protein (His tag)

PRM2 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318947
  • Target See all PRM2 Proteins
    PRM2 (Protamine 2 (PRM2))
    Protein Type
    Recombinant
    Origin
    • 10
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 12
    • 11
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This PRM2 protein is labelled with His tag.
    Purpose
    Recombinant Human Protamine-2/PRM2 Protein (His Tag)
    Sequence
    Met 1-Phe389
    Characteristics
    Recombinant Human Ribonucleotide Reductase Small Chain is produced by our Mammalian expression system and the target gene encoding Met1-Phe389 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PRM2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    PRM2 (Protamine 2 (PRM2))
    Alternative Name
    Protamine-2/PRM2 (PRM2 Products)
    Synonyms
    CT94.2 Protein, AI528784 Protein, Prm-2 Protein, PROTA2 Protein, P2 Protein, protamine 2 Protein, PRM2 Protein, Prm2 Protein
    Background

    Background: Ribonucleoside-Diphosphate Reductase Subunit M2 (RRM2) belongs to the ribonucleoside diphosphate reductase small chain family. The reductase of RRM2 catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. RRM2 supplies the precursors essential for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Phosphorylation on Ser-20 relieves the inhibitory effect on Wnt signaling.

    Synonym: Ribonucleoside-Diphosphate Reductase Subunit M2, Ribonucleotide Reductase Small Chain, Ribonucleotide Reductase Small Subunit, RRM2, RR2

    Molecular Weight
    45.9 kDa
    UniProt
    P31350
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