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PROS1 Protein (His tag)

PROS Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7197584
  • Target See all PROS1 (PROS) Proteins
    PROS1 (PROS) (Protein S (PROS))
    Protein Type
    Recombinant
    Origin
    • 7
    • 4
    • 1
    Human
    Source
    • 6
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PROS1 protein is labelled with His tag.
    Purpose
    Recombinant Human PROS1/Protein S Protein (His Tag)
    Sequence
    Met 1-Ser676
    Characteristics
    A DNA sequence encoding the human PROS1 (P07225) (Met1-Ser676) was expressed with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PROS Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    PROS1 (PROS) (Protein S (PROS))
    Alternative Name
    PROS1 (PROS Products)
    Synonyms
    PROS Protein, PS21 Protein, PS22 Protein, PS23 Protein, PS24 Protein, PS25 Protein, PSA Protein, THPH5 Protein, THPH6 Protein, zgc:154001 Protein, AW214361 Protein, protein S Protein, protein S (alpha) Protein, PROS1 Protein, Pros1 Protein, pros1 Protein
    Background

    Background: PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free, functionally active form and an inactive form complexed with C4b-binding protein. Besides its anticoagulant function, PROS1 also acts as an agonist for the tyrosine kinase receptors Tyro3, Axl, and Mer. The endothelium expresses Tyro3, Axl, and Mer and produces protein S. The interaction of protein S with endothelial cells and particularly its effects on angiogenesis have not yet been analyzed.

    Synonym: PROS,Protein S,PS21,PS22,PS23,PS24,PS25,PSA,THPH5,THPH6

    Molecular Weight
    74.1 kDa
    UniProt
    P07225
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