PROS1 Protein (His tag)
Quick Overview for PROS1 Protein (His tag) (ABIN7197584)
Target
See all PROS1 (PROS) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This PROS1 protein is labelled with His tag.
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Purpose
- Recombinant Human PROS1/Protein S Protein (His Tag)
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Sequence
- Met 1-Ser676
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Characteristics
- A DNA sequence encoding the human PROS1 (P07225) (Met1-Ser676) was expressed with a polyhistidine tag at the C-terminus.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Protein S (PROS) (AA 419-516) protein (GST tag)
PROS Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
Protein S (PROS) (AA 1-676) protein (GST tag)PROS Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
Protein S (PROS) protein (Myc-DYKDDDDK Tag)PROS Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- PROS1 (PROS) (Protein S (PROS))
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Alternative Name
- PROS1
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Background
- PROS,PS21,PS22,PS23,PS24,PS25,PSA,Protein S,THPH5,THPH6,PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free, functionally active form and an inactive form complexed with C4b-binding protein. Besides its anticoagulant function, PROS1 also acts as an agonist for the tyrosine kinase receptors Tyro3, Axl, and Mer. The endothelium expresses Tyro3, Axl, and Mer and produces protein S. The interaction of protein S with endothelial cells and particularly its effects on angiogenesis have not yet been analyzed.
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Molecular Weight
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Calculated MW: 74.1 kDa
Observed MW: 69-89 kDa
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Gene ID
- 5627
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UniProt
- P07225
Target
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