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RNASET2 Protein (His tag)

Recombinant RNASET2 protein expressed in Baculovirus infected Insect Cells.
Catalog No. ABIN7197719

Quick Overview for RNASET2 Protein (His tag) (ABIN7197719)

Target

See all RNASET2 Proteins
RNASET2 (Ribonuclease T2 (RNASET2))

Protein Type

Recombinant

Origin

  • 7
  • 3
  • 2
  • 1
Human

Source

  • 8
  • 2
  • 1
  • 1
  • 1
Baculovirus infected Insect Cells

Purity

> 98 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This RNASET2 protein is labelled with His tag.

    Purpose

    Recombinant Human RNASET2 Protein (Baculovirus, His Tag)

    Sequence

    Met 1-His 256

    Characteristics

    A DNA sequence encoding the human RNASET2 isoform 1 (O00584-1) (Met 1-His 256) was fused with a polyhistidine tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    RNASET2 (Ribonuclease T2 (RNASET2))

    Alternative Name

    RNASET2

    Background

    Background: RNASET2 (ribonuclease T2) is an enzyme which belongs to the RNase T2 family. It is highly expressed in the temporal lobe and fetal brain. RNASET2 gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. Defects in RNASET2 are the cause of leukoencephalopathy cystic without megalencephaly. An infantile-onset syndrome of cerebral leukoencephalopathy. Affected newborns develop microcephaly and neurologic abnormalities including psychomotor impairment, seizures and sensorineural hearing impairment. The brain shows multifocal white matter lesions, anterior temporal lobe subcortical cysts, pericystic abnormal myelination, ventriculomegaly and intracranial calcifications.

    Synonym: Ribonuclease T2,3.1.27.-,Ribonuclease 6,RNASE6PL

    Molecular Weight

    28.5 kDa
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