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RPS19 Protein

This Recombinant RPS19 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318112

Quick Overview for RPS19 Protein (ABIN7318112)

Target

See all RPS19 Proteins
RPS19 (Ribosomal Protein S19 (RPS19))

Protein Type

Recombinant

Origin

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Human

Source

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Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purpose

    Recombinant Human RPS19 Protein

    Sequence

    Pro2-His145

    Characteristics

    Recombinant Human 40S Ribosomal Protein S19 is produced by our E.coli expression system and the target gene encoding Pro2-His145 is expressed.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    RPS19 (Ribosomal Protein S19 (RPS19))

    Alternative Name

    RPS19

    Background

    Background: 40S Ribosomal Protein S19 (RPS19) is a ribosomal protein that Belongs to the ribosomal protein S19e family. RPS19 is located in the nucleoli, and higher level expression is seen in colon carcinoma tissue than normal colon tissue. It required for pre-rRNA processing and maturation of 40S ribosomal subunits. RPS19 plays a role in many biological processes, such as endocrine pancreas development, erythrocyte differentiation, mRNA metabolic process. Defects in RPS19 are the cause of Diamond-Blackfan anemia type 1 (DBA1), which is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy.

    Synonym: 40S Ribosomal Protein S19, RPS19

    Molecular Weight

    16.1 kDa

    UniProt

    P39019

    Pathways

    Positive Regulation of Immune Effector Process, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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