RPS19 Protein (AA 1-145) (His tag)
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- Target See all RPS19 Proteins
- RPS19 (Ribosomal Protein S19 (RPS19))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-145
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RPS19 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMPGVTVK DVNQQEFVRA LAAFLKKSGK LKVPEWVDTV KLAKHKELAP YDENWFYTRA ASTARHLYLR GGAGVGSMTK IYGGRQRNGV MPSHFSRGSK SVARRVLQAL EGLKMVEKDQ DGGRKLTPQG QRDLDRIAGQ VAAANKKH
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product RPS19 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.2M NaCl, 40 % glycerol, 2 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- RPS19 (Ribosomal Protein S19 (RPS19))
- Alternative Name
- RPS19 (RPS19 Products)
- Synonyms
- DBA Protein, DBA1 Protein, S19 Protein, Dsk3 Protein, 30S ribosomal protein S19 Protein, 40S ribosomal protein S19 Protein, ribosomal protein S19 Protein, rps19 Protein, rps-19 Protein, RPS19 Protein, Rps19 Protein
- Background
- RPS19 belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. Recombinant human RPS19 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 18.4kDa (168aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_001013
- UniProt
- P39019
- Pathways
- Positive Regulation of Immune Effector Process, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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