S100A13 Protein (AA 2-98)

Catalog No. ABIN7319336

This Recombinant S100A13 protein is produced in Escherichia coli (E. coli).

Quick Overview for S100A13 Protein (AA 2-98) (ABIN7319336)

Target: S100A13 (S100 Calcium Binding Protein A13 (S100A13))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 2-98

Purpose: Recombinant Human S100A13 Protein

Sequence: Ala2-Lys98

Characteristics: Recombinant Human Protein S100-A13 is produced by our E.coli expression system and the target gene encoding Ala2-Lys98 is expressed.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 1 mM CaCl₂, 0.1 % Tween-20, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: S100A13 (S100 Calcium Binding Protein A13 (S100A13))

Alternative Name: S100A13

Background: Protein S100-A13,S100 calcium-binding protein A13,S100A13,S100A13 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. It is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. It plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. It binds two calcium ions per subunit and one copper ion. Binding of one copper ion does not interfere with calcium binding. It is required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine.

Molecular Weight:

Calculated MW: 11.3 kDa

Observed MW: 12-15 kDa

NCBI Accession: NP_001019381

Pathways: S100 Proteins