S100A6 Protein

Catalog No. ABIN7317715

This Recombinant S100A6 protein is produced in Escherichia coli (E. coli).

Quick Overview for S100A6 Protein (ABIN7317715)

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purpose: Recombinant Human S100A6 Protein

Sequence: Met 1-Gly 90

Characteristics: A DNA sequence encoding the human S100A6 (NP_055439.1) (Met 1-Gly 90) was expressed.

Sterility: 0.2 μm filtered

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Alternative Name: S100A6

Background: 2A9,5B10,CABP,CACY,Calcyclin,Growth factor-inducible protein 2A9,MLN 4,PRA,Prolactin receptor-associated protein,Protein S100-A6,S100 calcium-binding protein A6,S100A6,S100 proteinis a family of low molecular weight protein found in vertebrates characterized by twoEF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is100 % soluble in ammonium sulfateat neutral pH . Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from theneural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. S100A6 (S100 calcium binding protein A6) is a member of the S100 family of proteins, and functions in prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of S100A6 have been implicated in melanoma.

Molecular Weight:

Calculated MW: 10.2 kDa

Observed MW: 10 kDa

Gene ID: 6277

NCBI Accession: NP_055439

UniProt: P06703

Pathways: S100 Proteins