SCGB3A2 Protein (AA 22-93)

Catalog No. ABIN7319165

This Recombinant SCGB3A2 protein is expressed in Escherichia coli (E. coli).

Quick Overview for SCGB3A2 Protein (AA 22-93) (ABIN7319165)

Target: SCGB3A2 (Secretoglobin, Family 3A, Member 2 (SCGB3A2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 22-93

Purpose: Recombinant Human UGRP1 Protein

Sequence: Phe22-Val93

Characteristics: Recombinant Human Uteroglobin-Related Protein 1 is produced by our E.coli expression system and the target gene encoding Phe22-Val93 is expressed.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: SCGB3A2 (Secretoglobin, Family 3A, Member 2 (SCGB3A2))

Alternative Name: UGRP1

Background: PNSP1,PnSP-1,Pneumo Secretory Protein 1,SCGB3A2,Secretoglobin Family 3A Member 2,UGRP1,Uteroglobin-Related Protein 1,Uteroglobin-Related Protein 1 (UGRP1) belongs to the secretoglobin family which has been suggested to play a role in lung inflammation and allergic diseases. UGRP1 is a 17 kDa secreted homodimeric protein that shows amino acid sequence similarity with uteroglobin. UGRP1 is expressed predominantly in the lung and low levels of expression are detected in the thyroid. Expression of UGRP1 in lung epithelial cells is enhanced by IL-10 and decreased through the activities of IL-9 and IL-5. UGRP1 interacts with the macrophage scavenger receptor with collagenous structure which is expressed by alveolar macrophages in the lung. It have suggested that UGRP1 may be involved in inflammation and pathogen clearance in the lung by binding to its receptor.

Molecular Weight:

Calculated MW: 7.9 kDa

Observed MW: 6&7 kDa

Gene ID: 117156

UniProt: Q96PL1