SCG3 Protein (His tag)

Catalog No. ABIN7320015

This Recombinant SCG3 protein is produced in HEK-293 Cells.

Quick Overview for SCG3 Protein (His tag) (ABIN7320015)

Target: SCG3 (Secretogranin III (SCG3))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 95 % as determined by SDS-PAGE

Product Details

Purification tag / Conjugate: This SCG3 protein is labelled with His tag.

Purpose: Recombinant Mouse SCG3/Secretogranin 3 Protein (His Tag)

Sequence: Met1-Leu471

Characteristics: A DNA sequence encoding the mouse Scg3 (NP_033156.1) (Met1-Leu471) was expressed with a polyhistidine tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: SCG3 (Secretogranin III (SCG3))

Alternative Name: SCG3/Secretogranin 3

Background:

Background: SCG3, also known as secretogranin 3, is a member of the chromogranin/secretogranin family. Members of this family may serve as precursors for biologically active peptides. SCG3 is transported to secretory granules (SGs) in neuroendocrine cells. SCG3 binds strongly to chromogranin A (CgA) in an intragranular milieu and targets CgA to SGs in pituitary and pancreatic endocrine cells. With a sucrose density gradient of rat insulinoma-derived INS-1 cell homogenates, SgIII is localized to the SG fraction and is fractionated to the SG membrane (SGM) despite lacking the transmembrane region.

Synonym: 1B1075,AI385542,Chgd,SgIII

Molecular Weight: 52.4 kDa

NCBI Accession: NP_033156