SRPK3 Protein (His-GST)

Catalog No. ABIN7317409

This Recombinant SRPK3 protein is expressed in Baculovirus infected Insect Cells.

Quick Overview for SRPK3 Protein (His-GST) (ABIN7317409)

Target: SRPK3 (serine/arginine-Rich Protein Specific Kinase 3 (SRPK3))

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Purity: > 85 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This SRPK3 protein is labelled with His-GST.

Purpose: Recombinant Human STK23/MSSK1/SRPK3 Protein (His & GST Tag)

Sequence: Met 1-Pro 566

Characteristics: A DNA sequence encoding full length of human SRPK3 isoform 2 (NP_001164231.1) (Met 1-Pro 566) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: SRPK3 (serine/arginine-Rich Protein Specific Kinase 3 (SRPK3))

Alternative Name: STK23/MSSK1/SRPK3

Background: MGC102944,MSSK-1,MSSK1,STK23,Serine / threonine-protein kinase SRPK3, also known as Muscle-specific serine kinase 1, Serine/arginine-rich protein-specific kinase 3, SR-protein-specific kinase 3, Serine / threonine-protein kinase 23, MSSK-1, SRPK3 and MSSK1, is a member of the protein kinase superfamily and CMGC Ser / Thr protein kinase family. SRPK3 is a protein kinase belonging to serine/arginine protein kinases (SRPK) family, which phosphorylates serine / arginine repeat-containing proteins, and is controlled by a muscle-specific enhancer directly regulated by MEF2. SRPK3 / MSSK1 contains oneprotein kinase domain. SRPK3 / MSSK1 is exclusively expressed in skeletal and heart muscle. It is required for normal muscle development. Myocyte enhancer factor 2 (MEF2) plays essential roles in transcriptional control of muscle development. Normal muscle growth and homeostasis require MEF2-dependent signaling by SRPK3.

Molecular Weight:

Calculated MW: 89.7 kDa

Observed MW: 100 kDa

Gene ID: 26576

NCBI Accession: NP_001164231

UniProt: Q9UPE1