SLAMF6 Protein
Quick Overview for SLAMF6 Protein (ABIN7317455)
Target
See all SLAMF6 ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Human SLAMF6/Ly108 Protein
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Sequence
- Met 1-Met226
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Characteristics
- A DNA sequence encoding the human SLAMF6 (Q96DU3-1)(Met1-Met226) was expressed with six amino acids (LEVLFQ) at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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SLAM Family Member 6 (SLAMF6) (AA 22-226) protein (Fc Tag)
SLAMF6 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
SLAM Family Member 6 (SLAMF6) (AA 22-226) protein (His-Avi Tag)SLAMF6 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
SLAM Family Member 6 (SLAMF6) (AA 20-225) protein (His tag)SLAMF6 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
SLAM Family Member 6 (SLAMF6) (AA 22-226) protein (mFc-His Tag)SLAMF6 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
SLAM Family Member 6 (SLAMF6) (AA 1-271) protein (GST tag)SLAMF6 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
SLAM Family Member 6 (SLAMF6) (AA 22-226) protein (His tag)SLAMF6 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS
SLAM Family Member 6 (SLAMF6) protein (His tag)SLAMF6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
SLAM Family Member 6 (SLAMF6) (Active) protein (His tag)SLAMF6 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- SLAMF6 (SLAM Family Member 6 (SLAMF6))
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Alternative Name
- SLAMF6/Ly108
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Background
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Background: SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly108, is a single-pass type I membrane protein which belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly108 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly108 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly108 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly108 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly108 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.
Synonym: SLAM Family Member 6, Activating NK Receptor, NK-T-B-Antigen, NTB-A, CD352, SLAMF6, KALI, Ly108, NTBA, SF2000
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Molecular Weight
- 23.9 kDa
Target
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