ST8SIA1 Protein (AA 49-356) (His tag)

Catalog No. ABIN7319204

This Recombinant ST8SIA1 protein is expressed in HEK-293 Cells.

Quick Overview for ST8SIA1 Protein (AA 49-356) (His tag) (ABIN7319204)

Target: ST8SIA1 (ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 1 (ST8SIA1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 49-356

Purification tag / Conjugate: This ST8SIA1 protein is labelled with His tag.

Purpose: Recombinant Human ST8SIA1 Protein (His Tag)

Sequence: Tyr49-Ser356

Characteristics: Recombinant Human alpha-N-Acetylneuraminide alpha-2,8-Sialyltransferase is produced by our Mammalian expression system and the target gene encoding Tyr49-Ser356 is expressed with a 6His tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: ST8SIA1 (ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 1 (ST8SIA1))

Alternative Name: ST8SIA1

Background: 8-Sialyltransferase,8-Sialyltransferase 8A,Alpha-2,Alpha-N-Acetylneuraminide Alpha-2,Ganglioside GD3 Synthase,Ganglioside GT3 Synthase,SIAT8,SIAT8-A,SIAT8A,ST8SIA1,ST8SiaI,Sialyltransferase 8A,Sialytransferase St8Sia I,α-N-Acetylneuraminide α-2,8-Sialyltransferase (ST8SIA1) belongs to the glycosyltransferase 29 family. ST8SIA1 is a sialytransferase that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce GD3 and GT3. ST8SIA1 is highly expressed in melanoma cell lines, adult and fetal brain, low expressed in adult and fetal lung. ST8SIA1 may act as a type II transmembrane protein with a short N-termianl cytoplasmic domain and a single-pass transmembrane domain folowed by an enzymatic domain in the lument of the Golgi apparatus.

Molecular Weight:

Calculated MW: 36.2 kDa

Observed MW: 48 kDa

Gene ID: 6489

UniProt: Q92185