SENP7 Protein (AA 695-864)
This Recombinant SENP7 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7319010
$307.73
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Quick Overview for SENP7 Protein (AA 695-864) (ABIN7319010)
Target
See all SENP7 Proteins
SENP7
(SUMO1/sentrin Specific Protease 7 (SENP7))
Protein Type
Recombinant
Origin
Human
Source
Escherichia coli (E. coli)
Purity
> 95 % as determined by reducing SDS-PAGE.
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Protein Characteristics
- AA 695-864
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Purpose
- Recombinant Human SENP7 Protein
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Sequence
- Met695-Ala864
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Characteristics
- Recombinant Human Sentrin-Specific Protease 7 is produced by our E.coli expression system and the target gene encoding Met695-Ala864 is expressed with a 6His tag at the N-terminus.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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SUMO1/sentrin Specific Protease 7 (SENP7) (Transcript Variant 2) protein (His tag)
SENP7 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 5 % Glycerol, pH 7.4.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Expiry Date
- 6 months
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- SENP7 (SUMO1/sentrin Specific Protease 7 (SENP7))
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Alternative Name
- SENP7
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Background
- KIAA1707,SENP7,SSP2,SUMO-1-Specific Protease 2,SUSP2,Sentrin-Specific Protease 7,Sentrin/SUMO-Specific Protease SENP7,Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPase-activating protein 1) but had limited activity against SUMO-1-modified RanGAP1.
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Molecular Weight
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Calculated MW: 19.8 kDa
Observed MW: 22 kDa
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Gene ID
- 57337
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UniProt
- Q9BQF6
Target
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