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alpha Taxilin Protein (His tag)

TXLNA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319208
  • Target See all alpha Taxilin (TXLNA) Proteins
    alpha Taxilin (TXLNA) (Taxilin alpha (TXLNA))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    Human
    Source
    • 4
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This alpha Taxilin protein is labelled with His tag.
    Purpose
    Recombinant Human TXLNA Protein (His Tag)
    Sequence
    Met 1-Lys162
    Characteristics
    Recombinant Human alpha-Taxilin is produced by our E.coli expression system and the target gene encoding Met1-Lys162 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TXLNA Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    alpha Taxilin (TXLNA) (Taxilin alpha (TXLNA))
    Alternative Name
    TXLNA (TXLNA Products)
    Synonyms
    fc21b12 Protein, im:7039434 Protein, wu:fc21b12 Protein, zgc:162882 Protein, TXLNA Protein, txlnb Protein, MGC154810 Protein, 2600010N21Rik Protein, AI425952 Protein, AW209241 Protein, Il14 Protein, Txln Protein, IL14 Protein, RP4-622L5.4 Protein, TXLN Protein, taxilin alpha Protein, taxilin alpha S homeolog Protein, txlna Protein, TXLNA Protein, txlna.S Protein, MCYG_06155 Protein, Txlna Protein
    Background

    Background: α-Taxilin belongs to the taxilin family. α-Taxilin exists in almost all tissues, with higher expression levels observed in the heart, kidney, liver, and pancreas. α-Taxilin binds to the C-terminal coiled coil region of syntaxin family members STX1A, STX3A, and STX4A, but not when these proteins are complexed with SNAP25, VAMP2 or STXBP1, suggesting that it interacts with syntaxins that do not form the SNARE complex. It is shown that α-Taxilin plays multiple roles in the generation and maintenance of neurons through modulation of the NAC-mediated translational machinary and/or the syntaxin-mediated vesicle traffic in the soma. In addition, α-Taxilin may be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.

    Synonym: Alpha-Taxilin, TXLNA, TXLN

    Molecular Weight
    20.4 kDa
    UniProt
    P40222
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