CD300LG Protein
Quick Overview for CD300LG Protein (ABIN7317256)
Target
See all CD300LG (TREM4) ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Human CLM-9/TREM4 Protein
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Sequence
- Met 1-Arg247
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Characteristics
- A DNA sequence encoding the human CD300LG (AAH25395.1)(Met1-Arg247) was expressed with six amino acids (LEVLFQ) at the C-terminus was expressed and purified.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- CD300LG (TREM4) (Triggering Receptor Expressed On Myeloid Cells 4 (TREM4))
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Alternative Name
- CLM-9/TREM4
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Background
- CD300 Antigen-Like Family Member G,CD300LG,CD300g,CLM-9,CLM9,CMRF35-Like Molecule 9,NEPMUCIN,TREM-4,TREM4,Triggering Receptor Expressed on Myeloid Cells 4,CLM-9, also known as TREM4, is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, microglia, and dendritic cells. CLM-9 may mediate L-selectin-dependent lymphocyte rollings. It binds SELL in a calcium dependent manner. CLM-9 also binds lymphocyte which suggests that it functions in lymphocyte adhesion. The major CLM-9 transcript is expressed highly in human heart, skeletal muscle, and placenta. The mouse protein has been shown to be expressed in capillary endothelial cells. Human CLM-9 mediates the uptake of human IgA2 and mouse IgM.
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Molecular Weight
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Calculated MW: 25.5 kDa
Observed MW: 61-66 kDa
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Gene ID
- 146894
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UniProt
- Q6UXG3
Target
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