TPM3 Protein
Quick Overview for TPM3 Protein (ABIN7319117)
Target
See all TPM3 ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Human Tropomyosin α-3 Chain/TPM3 Protein
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Sequence
- Met 1-Met248
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Characteristics
- Recombinant Human Tropomyosin alpha-3 Chain is produced by our E.coli expression system and the target gene encoding Met1-Met248 is expressed.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Tropomyosin 3 (TPM3) (AA 1-248) protein (GST tag)
TPM3 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
Tropomyosin 3 (TPM3) (AA 6-246) protein (His tag)TPM3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Tropomyosin 3 (TPM3) (AA 1-248) protein (His tag)TPM3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % SDS
Tropomyosin 3 (TPM3) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)TPM3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- TPM3 (Tropomyosin 3 (TPM3))
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Alternative Name
- Tropomyosin alpha-3 Chain/TPM3
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Background
- Gamma-Tropomyosin,TPM3,Tropomyosin Alpha-3 Chain,Tropomyosin-3,Tropomyosin-5,hTM5,Tropomyosin Alpha-3 Chain (TPM3) is a member of the Tropomyosin family. TPM3 exists as a heterodimer consisting of an alpha and a beta chain. TPM3 plays a central role in association with the Troponin complex and in the calcium dependent regulation of vertebrate striated muscle contraction. Defects in TPM3 are the cause of thyroid papillary carcinoma. Mutations in the TPM3 gene cause autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are linked with cancer.
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Molecular Weight
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Calculated MW: 29.0 kDa
Observed MW: 32 kDa
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Gene ID
- 7170
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UniProt
- P06753
Target
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