Ubiquitin B Protein (UBB) (GST-His-Tag)

Catalog No. ABIN7318921

This Recombinant Ubiquitin B protein is produced in Escherichia coli (E. coli).

Quick Overview for Ubiquitin B Protein (UBB) (GST-His-Tag) (ABIN7318921)

Target: Ubiquitin B (UBB)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This Ubiquitin B protein is labelled with GST-His-Tag.

Purpose: Recombinant Human Polyubiquitin-B/UBB Protein (GST&His Tag)

Sequence: Met 153-Gly228

Characteristics: Recombinant Human Poly-Ubiquitin chains is produced by our E.coli expression system and the target gene encoding Met153-Gly228 is expressed.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Ubiquitin B (UBB)

Alternative Name: Polyubiquitin-B/UBB

Background:

Background: Polyubiquitin-B(UBB) is one of Ubiquitins. Ubiquitin is one of the most conserved proteins known in eukaryotic organisms. Ubiquitin is required for ATP-dependent, non-lysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation.

Synonym: Polyubiquitin-B,UBB

Molecular Weight: 9.4 kDa

UniProt: P0CG47

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, Autophagy, EGFR Downregulation, Ubiquitin Proteasome Pathway