UBE2A Protein (GST-His-Tag)
Quick Overview for UBE2A Protein (GST-His-Tag) (ABIN7319273)
Target
See all UBE2A (ube2a) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This UBE2A protein is labelled with GST-His-Tag.
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Purpose
- Recombinant Human UBE2A Protein (GST & His Tag)
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Sequence
- Met 1-Cys152
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Characteristics
- Recombinant Human Ubiquitin-Conjugating Enzyme E2 A is produced by our E.coli expression system and the target gene encoding Met1-Cys152 is expressed with a GST, 6His tag at the N-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10 % Glycerol, pH 7.5.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- UBE2A (ube2a) (Ubiquitin-Conjugating Enzyme E2A (ube2a))
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Alternative Name
- UBE2A
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Background
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Background: Ubiquitin-Conjugating Enzyme E2 (UBE2A) is a member of the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2A catalyzes the covalent attachment of ubiquitin to other proteins. UBE2A is required for postreplication repair of UV-damaged DNA. UBE2A Interacts with RAD18 and WAC.
Synonym: Ubiquitin-Conjugating Enzyme E2 A, RAD6 Homolog A, HR6A, hHR6A, Ubiquitin Carrier Protein A, Ubiquitin-Protein Ligase A, UBE2A, RAD6A
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Molecular Weight
- 49.0 kDa
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UniProt
- P49459
Target
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