Uroplakin 2 Protein (UPK2) (His tag)
Quick Overview for Uroplakin 2 Protein (UPK2) (His tag) (ABIN7319162)
Target
See all Uroplakin 2 (UPK2) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Uroplakin 2 protein is labelled with His tag.
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Purpose
- Recombinant Human Uroplakin-2/UPK2 Protein (His Tag)
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Sequence
- Asp26-Gly155
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Characteristics
- Recombinant Human Uroplakin-2 is produced by our Mammalian expression system and the target gene encoding Asp26-Gly155 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Uroplakin 2 (UPK2)
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Alternative Name
- Uroplakin-2/UPK2
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Background
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Background: Uroplakin-2 is a single-pass type I membrane protein that belongs to the uroplakin-2 family. Uroplakin-2 is a component of the asymmetric unit membrane (AUM) and expressed in the ureter, a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. Uroplakin-2 forms heterodimer with UPK1A that is necessary for exiting out of the endoplasmic reticulum (ER). Uroplakin-2 may play an important role in regulating the assembly of the AUM. AUM is believed to strengthen the urothelium by preventing cell rupture during bladder distention.
Synonym: Uroplakin-2, UP2, Uroplakin II, UPII, UPK2
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Molecular Weight
- 14.8 kDa
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UniProt
- O00526
Target
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