Quick Overview for IFNAR1 Protein (His tag) (ABIN7320999)
Target
See all IFNAR1 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This IFNAR1 protein is labelled with His tag.
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Purpose
- Recombinant Rhesus macaque IFNAR1 Protein (His Tag)
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Sequence
- Ala25-Lys437
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Characteristics
- Recombinant Rhesus macaque IFNAR1 is produced by our Mammalian expression system and the target gene encoding Ala25-Lys437 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Interferon alpha/beta Receptor 1 (IFNAR1) (AA 28-436) protein (His tag)
IFNAR1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interferon alpha/beta Receptor 1 (IFNAR1) (AA 28-436) protein (Fc Tag)IFNAR1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interferon alpha/beta Receptor 1 (IFNAR1) (AA 28-436) protein (mFc Tag)IFNAR1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interferon alpha/beta Receptor 1 (IFNAR1) (AA 28-127) protein (GST tag)IFNAR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon alpha/beta Receptor 1 (IFNAR1) (AA 1-557) protein (GST tag)IFNAR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon alpha/beta Receptor 1 (IFNAR1) (Active) protein (His tag)IFNAR1 Origin: Mouse Host: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE Active
Interferon alpha/beta Receptor 1 (IFNAR1) (AA 27-429) protein (His tag)IFNAR1 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS
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Comment
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70-120 kDa
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
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Alternative Name
- IFNAR1
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Background
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Background: Interferon?alpha/beta receptor 1 (IFN? alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphorylation at Tyr-466. It also interacts with FBXW11, the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.
Synonym: Alpha-type antiviral protein, AVP, beta-type antiviral protein, CRF2-1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC, IFN-alpha/beta R1, IFN-alpha/beta receptor 1, IFN-alpha-REC, IFNAR, IFNAR1, IFN-aR1, IFNBR, IFNbR1, IFN-bR1, IFN-R-1
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Molecular Weight
- 48.4 kDa
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UniProt
- H9FTY3
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Pathways
- JAK-STAT Signaling, Hepatitis C
Target
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