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TNNC1 Protein

This Recombinant TNNC1 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7317698

Quick Overview for TNNC1 Protein (ABIN7317698)

Target

See all TNNC1 Proteins
TNNC1 (Cardiac Troponin C (TNNC1))

Protein Type

Recombinant

Origin

  • 10
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 90 % as determined by reducing SDS-PAGE.
  • Purpose

    Recombinant Human Troponin C/TNNC1 Protein

    Sequence

    Met 1-Glu161

    Characteristics

    A DNA sequence encoding the human TNNC1 (NP_003271.1) (Met1-Glu161) was expressed and purified.

    Endotoxin Level

    Please contact us for more information.
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  • Comment

    20 kDa

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from sterile 150 mM NaCl, 10 mM Na2HPO4, pH 7.5

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    TNNC1 (Cardiac Troponin C (TNNC1))

    Alternative Name

    TNNC1

    Background

    Background: Troponin I, also known as TNNC1, is part of the troponin complex. This complex contains 3 subunits: troponin I (TnI), troponin T (TnT) and troponin C (TnC). Troponin I is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.

    Synonym: CMD1Z,CMH13,TN-C,TNC,TNNC

    Molecular Weight

    18.4 kDa

    NCBI Accession

    NP_003271
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