TNNC1 Protein (His tag)
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- Target See all TNNC1 Proteins
- TNNC1 (Cardiac Troponin C (TNNC1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TNNC1 protein is labelled with His tag.
- Purpose
- Recombinant Human Troponin C/TNNC1 Protein (His Tag)
- Sequence
- Met1-Glu161
- Characteristics
- Recombinant Human Troponin C is produced by our E.coli expression system and the target gene encoding Met1-Glu161 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TNNC1 Protein
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Cardiac Troponin C (TNNC1) (AA 1-161) protein (GST tag)
TNNC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cardiac Troponin C (TNNC1) (AA 1-161) protein (Strep Tag)Crystallography grade TNNC1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Cardiac Troponin C (TNNC1) protein (DYKDDDDK Tag)TNNC1 Origin: Human Host: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Cardiac Troponin C (TNNC1) protein (Myc-DYKDDDDK Tag)TNNC1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Comment
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17-20 kDa
- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,100 mM NaCl,1 mM DTT,10 % glycerol, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- TNNC1 (Cardiac Troponin C (TNNC1))
- Alternative Name
- TNNC1 (TNNC1 Products)
- Synonyms
- CMD1Z Protein, CMH13 Protein, TN-C Protein, TNC Protein, TNNC Protein, cTnC Protein, tnnc1 Protein, zgc:103465 Protein, PCTNC1 Protein, cmd1z Protein, cmh13 Protein, tnc Protein, tnnc Protein, MGC80066 Protein, TNNC1 Protein, AI874626 Protein, TnC Protein, cTnI Protein, tncc Protein, Tncc Protein, stnnc Protein, zgc:86932 Protein, troponin C1, slow skeletal and cardiac type Protein, troponin C type 1a (slow) Protein, troponin C type 1 (slow) L homeolog Protein, cardiac troponin C Protein, troponin C, cardiac/slow skeletal Protein, troponin C type 1b (slow) Protein, TNNC1 Protein, tnnc1a Protein, tnnc1.L Protein, tnnc1 Protein, Tnnc1 Protein, tnnc1b Protein
- Background
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Background: Troponin I, also known as TNI, is a 24 kDa component of a protein complex on striated muscle thin filaments.Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. Troponin I inhibits the calcium-dependent muscle contraction mediated by Troponins C and T. The expression of cardiac Troponin I (TNNI3) is restricted to cardiac muscle, while TNNI1 and TNNI2(encoded by distinct genes) are expressed in skeletal muscle. Mutations of cardiac Troponin I are associated with heriditary cardiomyopathy. Human cardiac Troponin I shares 93 % amino acid sequence identity with mouse and rat cardiac Troponin I.
Synonym: CMD1Z,CMH13,TN-C,TNC,TNNC
- Molecular Weight
- 19.8 kDa
- UniProt
- P63316
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