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FGL1 Protein (Biotin)

This Recombinant FGL1 protein is produced in Human Cells.
Catalog No. ABIN7319770

Quick Overview for FGL1 Protein (Biotin) (ABIN7319770)

Target

See all FGL1 Proteins
FGL1 (Fibrinogen-Like 1 (FGL1))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 27
  • 6
  • 4
  • 4
  • 3
  • 1
Human

Source

  • 26
  • 9
  • 5
  • 2
  • 1
  • 1
Human Cells

Purity

>90 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This FGL1 protein is labelled with Biotin.

    Purpose

    Recombinant Human FGL1 (C-Fc-Avi) Biotinylated

    Sequence

    Leu23-Ile312

    Characteristics

    Biotinylated Recombinant Human Fibrinogen-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu23-Ile312 is expressed with a Fc, Avi tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.

    Biological Activity Comment

    Immobilized Mouse LAG-3-His(Cat#CK56) at 2μg/ml (100 μl/well) can bind Biotinylated Human FGL1-Avi(Cat#CY19). The ED50 of Human FGL1-Avi(Cat#CY19) is 0.08ug/ml.
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  • Comment

    60 kDa

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, 5 % Trehalose, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    FGL1 (Fibrinogen-Like 1 (FGL1))

    Alternative Name

    FGL1

    Background

    Background: Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 .

    Synonym: Fibrinogen-like protein 1, FGL1, HP-041, Hepassocin, HFREP-1, LFIRE-1

    Molecular Weight

    62.7 kDa

    UniProt

    Q08830
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