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IL-1b/IL-1 beta/il-1F2 (AA 115-266) protein (His tag)

This Recombinant IL-1b/IL-1 beta/il-1F2 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7321016
$307.73
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Quick Overview for IL-1b/IL-1 beta/il-1F2 (AA 115-266) protein (His tag) (ABIN7321016)

Target

IL-1b/IL-1 beta/il-1F2

Protein Type

Recombinant

Origin

Guinea Pig

Source

Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 115-266

    Purification tag / Conjugate

    His tag

    Purpose

    Recombinant Cavia porcellus IL-1b/IL-1 beta/IL-1F2 Protein (His Tag)

    Sequence

    Thr115-Ser266

    Characteristics

    Recombinant Cavia porcellus Interleukin-1 Beta is produced by our E.coli expression system and the target gene encoding Thr115-Ser266 is expressed with a 6His tag at the C-terminus.

    Sterility

    0.2 μm filtered

    Endotoxin Level

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    IL-1b/IL-1 beta/il-1F2

    Background

    IL1F,catabolin,Il-1b,IL1-BETA,IL-1beta,IL1F2,Il1b,Interleukin-1 beta,IL-1 beta,Interleukin-1 beta (IL1B) belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells.

    Molecular Weight

    Calculated MW: 18.2 kDa

    Observed MW: 16-19 kDa

    UniProt

    Q9WVG1
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