IL-1b/IL-1 beta/il-1F2 (AA 115-266) protein (His tag)
Quick Overview for IL-1b/IL-1 beta/il-1F2 (AA 115-266) protein (His tag) (ABIN7321016)
Target
Protein Type
Origin
Source
Purity
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Protein Characteristics
- AA 115-266
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Purification tag / Conjugate
- His tag
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Purpose
- Recombinant Cavia porcellus IL-1b/IL-1 beta/IL-1F2 Protein (His Tag)
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Sequence
- Thr115-Ser266
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Characteristics
- Recombinant Cavia porcellus Interleukin-1 Beta is produced by our E.coli expression system and the target gene encoding Thr115-Ser266 is expressed with a 6His tag at the C-terminus.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- IL-1b/IL-1 beta/il-1F2
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Background
- IL1F,catabolin,Il-1b,IL1-BETA,IL-1beta,IL1F2,Il1b,Interleukin-1 beta,IL-1 beta,Interleukin-1 beta (IL1B) belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells.
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Molecular Weight
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Calculated MW: 18.2 kDa
Observed MW: 16-19 kDa
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UniProt
- Q9WVG1
Target
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