Annexin A2 Protein (ANXA2) (AA 2-339) (His tag)
Quick Overview for Annexin A2 Protein (ANXA2) (AA 2-339) (His tag) (ABIN7273844)
Target
See all Annexin A2 (ANXA2) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 2-339
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Purification tag / Conjugate
- This Annexin A2 protein is labelled with His tag.
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Purpose
- Human ANXA2 Protein
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Sequence
- Ser2-Asp339
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Characteristics
- Recombinant Human ANXA2 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Ser2-Asp339.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Annexin A2 (ANXA2) (AA 2-339) protein (His tag)
ANXA2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Annexin A2 (ANXA2) (AA 19-357) protein (GST tag)ANXA2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Annexin A2 (ANXA2) (AA 1-339) protein (GST tag)ANXA2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Annexin A2 (ANXA2) (AA 186-268) protein (GST tag)ANXA2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Annexin A2 (ANXA2) (AA 2-339) protein (His tag)ANXA2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Annexin A2 (ANXA2) (AA 2-339) protein (His tag)ANXA2 Origin: Dog Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Annexin A2 (ANXA2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)ANXA2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- Annexin A2 (ANXA2)
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Alternative Name
- ANXA2
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Background
- ANXA2, highly expressed in invasive breast cancer cells, is closely related with poor prognosis, and acts as a molecular switch to EGFR activation. ANXA2 expression is inversely correlated with cell sensitivity to gefitinib. Knockdown of ANXA2 expression in MDA-MB-231 cells increased the gefitinib induced cell death. When ANXA2 was overexpressed in MCF7 cells, the gefitinib induced cell death was decreased. Furthermore, the phosphorylation of ANXA2 at Tyr23 is negatively correlated with the sensitivity of TNBC to gefitinib.
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Molecular Weight
- 39.6 kDa same as Tris-Bis PAGE result.
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UniProt
- P07355
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Pathways
- S100 Proteins
Target
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