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CD180 Protein (AA 21-626) (His tag)

CD180 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274092
  • Target See all CD180 Proteins
    CD180 (CD180 Molecule (CD180))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 21-626
    Origin
    • 4
    • 3
    Mouse
    Source
    • 4
    • 3
    HEK-293 Cells
    Purification tag / Conjugate
    This CD180 protein is labelled with His tag.
    Purpose
    Mouse CD180 Protein
    Sequence
    Thr21-Ser626
    Characteristics
    Recombinant Mouse CD180 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr21-Ser626.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CD180 (CD180 Molecule (CD180))
    Alternative Name
    CD180 (CD180 Products)
    Synonyms
    Ly78 Protein, CD180 Protein, LY64 Protein, RP105 Protein, F630107B15 Protein, CD180 molecule Protein, CD180 antigen Protein, Cd180 Protein, CD180 Protein
    Background
    CD180, a related member of the Toll-like receptor family, is lost or underexpressed at the plasma membrane in circulating cells of various B-cell lymphomas except marginal zone lymphomas (MZL).CD180 can be considered as a single positive robust marker of MZL and should be therefore included in flow cytometry panels for the diagnosis of mature B-cell neoplasms.
    Molecular Weight
    69.1 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.
    UniProt
    Q62192
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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