Adipsin Protein (AA 26-259) (Fc Tag)

Catalog No. ABIN7274336

Product Details

Target: Adipsin (CFD) (Complement Factor D (CFD))

Protein Type: Recombinant

Protein Characteristics: AA 26-259

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This Adipsin protein is labelled with Fc Tag.

Purpose: Mouse Complement Factor D/CFD Protein

Sequence: Ile26-Ser259

Characteristics: Recombinant Mouse Complement Factor D/CFD Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile26-Ser259.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in 20 mM Tris,500 mM NaCl ( pH 7.4).

Storage: -80 °C

Storage Comment: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Adipsin (CFD) (Complement Factor D (CFD))

Alternative Name: Complement Factor D (CFD Products)

Background: Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium.

Molecular Weight: 52.2 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

UniProt: P03953-1

Pathways: Complement System