EPH Receptor A2 Protein (EPHA2) (AA 24-534) (hFc Tag)

Catalog No. ABIN7274550

This Recombinant EPH Receptor A2 protein is produced in HEK-293 Cells.

Quick Overview for EPH Receptor A2 Protein (EPHA2) (AA 24-534) (hFc Tag) (ABIN7274550)

Target: EPH Receptor A2 (EPHA2)

Protein Type: Recombinant

Biological Activity: Active

Origin: Cynomolgus

Source: HEK-293 Cells

Purity: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Product Details

Protein Characteristics: AA 24-534

Purification tag / Conjugate: This EPH Receptor A2 protein is labelled with hFc Tag.

Purpose: Cynomolgus EPHA2 Protein

Sequence: Ala24-Ser534

Characteristics: Recombinant Cynomolgus EPHA2 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ala24-Ser534.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Cynomolgus EPHA2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Cynomolgus EPHA2 is greater than 95% as determined by SEC-HPLC.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: EPH Receptor A2 (EPHA2)

Alternative Name: EPHA2

Background: Ephrin type-A receptor 2 (EPHA2) is a receptor tyrosine kinase (RTK), whose over-expression has been observed in a variety of cancers, including breast cancer. EPHA2 expression may be causally related to tumorigenesis, therefore, it is important to understand how EPHA2 gene (EPHA2) expression is regulated.

Molecular Weight: 83.1 kDa. Due to glycosylation, the protein migrates to 90-100 kDa based on Bis-Tris PAGE result.

UniProt: Q1KL86

Pathways: RTK Signaling