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EPH Receptor A10 Protein (EPHA10) (AA 23-565) (His tag)

EPHA10 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274562
  • Target See all EPH Receptor A10 (EPHA10) Proteins
    EPH Receptor A10 (EPHA10)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 23-565
    Origin
    • 8
    • 3
    • 1
    Mouse
    Source
    • 6
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This EPH Receptor A10 protein is labelled with His tag.
    Purpose
    Mouse EPHA10 Protein
    Sequence
    Leu23-Ala565
    Characteristics
    Recombinant Mouse EPHA10 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu23-Ala565.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    EPH Receptor A10 (EPHA10)
    Alternative Name
    EPHA10 (EPHA10 Products)
    Synonyms
    A330090H18 Protein, RGD1562679 Protein, EPH receptor A10 Protein, Eph receptor A10 Protein, EPHA10 Protein, Epha10 Protein
    Background
    EphA10 (erythropoietin-producing hepatocellular carcinoma receptor A10) is a catalytically defective receptor protein tyrosine kinase in the ephrin receptor family.EphA10 was elevated and higher in tumor tissues than in normal tissues in some cancer types, including pancreatic cancer.EphA10 silencing reduced the proliferation, migration, and adhesion of MIA PaCa-2 and AsPC-1 pancreatic cancer cells. EphA10 plays a pivotal role in the tumorigenesis of pancreatic epithelial cells and is a novel therapeutic target for pancreatic cancer.
    Molecular Weight
    59.6 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.
    Pathways
    RTK Signaling
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