FAP Protein (His-Avi Tag,Biotin)
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- Target See all FAP Proteins
- FAP (Fibroblast Activation Protein, alpha (FAP))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FAP protein is labelled with His-Avi Tag,Biotin.
- Sequence
- Leu26-Asp760
- Purity
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Biotinylated Human FAP, His Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-FAP Antibody, hFc Tag with the EC50 of 17.6ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product FAP Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in 20 mM Tris, 150 mM NaCl, 200 mM L-arginine ( pH 8.2).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please do not repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- FAP (Fibroblast Activation Protein, alpha (FAP))
- Alternative Name
- FAP (FAP Products)
- Background
- FAP, FAPalpha, SIMP, Seprase, APCE, DPPIV, DPPIVA, FAPA,Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital in the malignant behaviors of cancer cells.
- Molecular Weight
- 87.9 kDa. Due to glycosylation, the protein migrates to 90-100 kDa based on Tris-Bis PAGE result.
- UniProt
- Q12884
- Pathways
- Tube Formation
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