Osteoactivin Protein (GPNMB) (AA 23-486) (His tag)
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- Target See all Osteoactivin (GPNMB) Proteins
- Osteoactivin (GPNMB)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-486
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Osteoactivin protein is labelled with His tag.
- Purpose
- Human Osteoactivin/GPNMB Protein
- Sequence
- Lys23-Asn486
- Characteristics
- Recombinant Human Osteoactivin/GPNMB Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Lys23-Asn486.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Osteoactivin (GPNMB) (AA 23-502) protein (His tag)
GPNMB Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Osteoactivin (GPNMB) (AA 23-496) protein (His tag)GPNMB Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Osteoactivin (GPNMB) (AA 1-572) protein (GST tag)GPNMB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Osteoactivin (GPNMB) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)GPNMB Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Osteoactivin (GPNMB)
- Alternative Name
- Osteoactivin (GPNMB Products)
- Background
- GPNMB is highly expressed in macrophages and microglia, which are cells involved with innate immune response in the periphery and the brain, respectively. Some studies have shown increased levels of GPNMB in pro-inflammatory conditions, such as LPS treatment, and in pathological conditions, such as neurodegenerative diseases and cancer.
- Molecular Weight
- 53.1 kDa. Due to glycosylation, the protein migrates to 78-98 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_002501
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