Osteoactivin Protein (GPNMB) (AA 22-486) (His tag)
Quick Overview for Osteoactivin Protein (GPNMB) (AA 22-486) (His tag) (ABIN7319322)
Target
See all Osteoactivin (GPNMB) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 22-486
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Purification tag / Conjugate
- This Osteoactivin protein is labelled with His tag.
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Purpose
- Recombinant Human GPNMB Protein (aa 22-486, His Tag)
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Sequence
- Ala22-Pro486
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Characteristics
- Recombinant Human Glycoprotein Non-Metastatic Melanoma Protein B is produced by our Mammalian expression system and the target gene encoding Ala22-Pro486 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Osteoactivin (GPNMB) (AA 23-502) (Active) protein (His tag)
GPNMB Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Osteoactivin (GPNMB) (AA 23-486) (Active) protein (His tag)GPNMB Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Osteoactivin (GPNMB) (AA 23-496) protein (His tag)GPNMB Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Osteoactivin (GPNMB) (AA 1-572) protein (GST tag)GPNMB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Osteoactivin (GPNMB) (AA 22-474) protein (His tag)GPNMB Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % SDS
Osteoactivin (GPNMB) (AA 22-474) protein (His tag)GPNMB Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS
Osteoactivin (GPNMB) protein (His tag)GPNMB Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Osteoactivin (GPNMB) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)GPNMB Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Osteoactivin (GPNMB)
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Alternative Name
- GPNMB
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Background
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Background: Osteoactivin is an intracellular glycoprotein belongs to the NMB/pMEL-17 family, which is asscociated with cell endosomal/lysomal compartments. Human Osteoactivin is a 560 amino acid type I transmembrane protein, and one alternate splice form shows a 12 amino acid insert between amino acid 339-340. An additional 206 amino acid isoform shows a mutation at position 181 that results in a 26 amino acid substitution for the C-terminal 380 amino acids. Cells knowns to express Osteoactivin include fibroblast, osteoblasts, myeloid dendritic cell, melanocytes, plus fetal chondrocytes and stratum basale keratinocytes, macrophages/keratinocytes.
Synonym: Transmembrane Glycoprotein NMB, Transmembrane Glycoprotein HGFIN, GPNMB, HGFIN,NMB,Osteoactivin
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Molecular Weight
- 53.1 kDa
Target
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