GP1BB Protein (AA 27-147) (hFc Tag)

Catalog No. ABIN7274757

This Recombinant GP1BB protein is produced in HEK-293 Cells.

Quick Overview for GP1BB Protein (AA 27-147) (hFc Tag) (ABIN7274757)

Target: GP1BB (Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB))

Protein Type: Recombinant

Biological Activity: Active

Origin: Mouse

Source: HEK-293 Cells

Purity: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Product Details

Protein Characteristics: AA 27-147

Purification tag / Conjugate: This GP1BB protein is labelled with hFc Tag.

Purpose: Mouse GP1BB Protein

Sequence: Pro27-Cys147

Characteristics: Recombinant Mouse GP1BB Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Pro27-Cys147.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Mouse GP1BB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Mouse GP1BB is greater than 95% as determined by SEC-HPLC.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: GP1BB (Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB))

Alternative Name: GP1BB

Background: The glycoprotein (GP) Ib-IX complex is the receptor on platelet surfaces that mediates their adhesion to subendothelium. It comprises three polypeptides (GP Ib alpha, GP Ib beta, GP IX), each of which belongs to a superfamily of proteins containing conserved leucine-rich motifs. Association between GP Ib alpha and GP Ib beta was demonstrated biochemically on immunoblots of detergent lysates of CHO alpha beta cells, electrophoresis under nonreducing conditions revealed the two subunits to be covalently linked through a disulfide bond.

Molecular Weight: 39.5 kDa. Due to glycosylation, the protein migrates to 46-50 kDa based on Bis-Tris PAGE result.

UniProt: P56400