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IL1A Protein (AA 113-271)

Recombinant IL1A protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN7274879

Quick Overview for IL1A Protein (AA 113-271) (ABIN7274879)

Target

See all IL1A Proteins
IL1A (Interleukin 1 alpha (IL1A))

Protein Type

Recombinant

Origin

  • 19
  • 14
  • 10
  • 5
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  • 3
  • 3
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  • 3
  • 3
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Human

Source

  • 44
  • 13
  • 11
  • 2
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • Protein Characteristics

    AA 113-271

    Purpose

    Human IL-1 alpha/IL-1A Protein

    Sequence

    Ser113-Ala271

    Characteristics

    Recombinant Human IL-1 alpha/IL-1A Protein is expressed from E.coli without tag.It contains Ser113-Ala271.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 0.05 EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    IL1A (Interleukin 1 alpha (IL1A))

    Alternative Name

    IL-1 alpha

    Background

    The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made in our understanding of biogenesis of IL-1β and its functions in human diseases.

    Molecular Weight

    18 kDa same as Tris-Bis PAGE result.

    NCBI Accession

    NP_000566

    Pathways

    NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
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